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Yeah look at the pros, all use them for resistance mid/late game, get a life down voters.
I just started using her last night after getting bored with main as Twitch since I go 32/3 no problem in
a full match. I'm running quint of fortitude, mark of deso, attack speed, and magic resist. Same almost as my twitch build. What I've noticed with vayne is if I rush black cleaver before infinity it stacks up great with her skills. Will continue to mess around with the item order personally but otherwise a very great guide.
Keep your chin up, sorry if I sounded like an ***, it just came as a shock to me :/
Good luck with your future Vayne games :3