AP GP works, you want a wota though so your ult gives you a ton of HP back in team fights... iv done AP GP b4 it's fun making oranges more op :D.
Lee Sin doesn't know what's happening. :D. And why is MF in friendly terms with GP, she should have a mean and disgusted look to GP, since she's suspecting that he's the AP Killer of her father, but she can't touch him because they're both in the League.
What's red, orange, yellow, green, blue, indigo, and violet at the same time? Rainbow
You do this when trolling. It's not seriously viable, but it does work for laughs.

http://www.mobafire.com/league-of-legends/build/duffs-336706
Come hang out when I'm streaming! http://www.twitch.tv/dufftime
I don't know. I guess you could hybrid GP. The idea that you have to rely so heavily on your oranges and ult is kind of garbage since the cool downs on those is probably going to make you more passive than you should be. I can see you doing some decent supporting, but the only AP item I would want to get on GP is Trinity's Force. Maybe Hextech Gunblade, but probably not. Also Zhonya's 2 second of invulnerability doesn't make up for you being squsihy, and getting HP from your oranges is great but I doubt the cool down well be low enough for you to use it again during the battle.
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-100HP--> DIE
Eats orange gets 1k health :3