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1. Double Desolation Runes sacrifices a lot of potential lane dominance. I'd suggest running atleast one set of strength runes, either the marks of the quintessences for the lane dominance, harassing, last hitting, etc. Also, just look at Q's scaling ratio with AD, take advantage of it.
2. I don't value greater seal of replenishment either, since you sacrifice some ability to trade with champions who run
3. Separate the coming Gameplay section into atleast Laning, and Teamfighting sections, since they're both significantly varied in how they're played and require specific strategies as a
Good luck with the remainder of your guide :D