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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 3 Guides // Other Patches
8.6
535
Votes
70
LoL Champion Swain Build Guide
LoL Champion Swain Build Guide

[ Patch 25.17 NEW SEASON 15 UPDATED!! ] - SWAIN is the GOD OF MIDLANE PAIN! - 🤯

Guide by RezoneVerified updated September 19, 2025
  • In-depth
8.3
651
Votes
54
LoL Champion Anivia Build Guide
LoL Champion Anivia Build Guide

👉 🧊[ NEW SEASON 15 ] - Master's Guide to Midlane ANIVIA! S TIER PICK! 🧊 👈

Guide by RezoneVerified updated September 10, 2025
  • In-depth
8.2
9
Votes
1
LoL Champion Qiyana Build Guide
LoL Champion Qiyana Build Guide

I'm not arrogant, I'm right Qiyana|25.18| GUIDE MID+JNG

Guide by Deylan updated September 13, 2025
8.1
11
Votes
2
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

2 Million Points - AP Katarina Build

Guide by Saddest updated September 18, 2025
  • In-depth
8
124
Votes
23
LoL Champion Aurora Build Guide
LoL Champion Aurora Build Guide

[ AURORA MIDLANE GUIDE SEASON 16 - 25.18 🐰[AURORA IS THE MOST ANNOYING MIDLANER 2025]

Guide by RezoneVerified updated September 16, 2025
  • In-depth
7.7
86
Votes
18
LoL Champion Tryndamere Build Guide
LoL Champion Tryndamere Build Guide

Step1v9 Tryndamere Guide

Guide by step1v9 updated September 22, 2025
  • In-depth
7.4
24
Votes
9
LoL Champion Irelia Build Guide
LoL Champion Irelia Build Guide

[25.18] SkandaLoL's AP Irelia Ultimate Guide

Guide by SkandalloTV updated September 21, 2025
  • In-depth
  • Off-Meta
7.3
84
Votes
27
LoL Champion Zeri Build Guide
LoL Champion Zeri Build Guide

[25.18] ⚡️Get Zapped⚡️Zeri Ap Oneshot Build

Guide by Bambado updated September 14, 2025
Rating Pending
LoL Champion Ahri Build Guide
LoL Champion Ahri Build Guide

Textwall Tryhard Ahri guide by Streetmagiks

Guide by streetmagiks updated September 13, 2025
  • In-depth
Rating Pending
LoL Champion Quinn Build Guide
LoL Champion Quinn Build Guide

Winged Victory: Dominate Mid with Quinn 🦅

Guide by Quinfrey updated September 23, 2025
  • In-depth
6.3
6
Votes
5
LoL Champion Mel Build Guide
LoL Champion Mel Build Guide

[S15] Arcane AP Mid/Bot ♡

Guide by millysenpai updated September 11, 2025
  • In-depth
Rating Pending
LoL Champion Pyke Build Guide
LoL Champion Pyke Build Guide

Supports in Mid

Guide by .DOT updated September 19, 2025
  • Off-Meta
New Guide
LoL Champion Anivia Build Guide
LoL Champion Anivia Build Guide

Anivia Guide [OLD - S12]

Guide by sidromest updated September 18, 2025
  • In-depth
New Guide
LoL Champion Yone Build Guide
LoL Champion Yone Build Guide

yone guide(silence blade)

Guide by silence blade updated September 16, 2025
10
603
Votes
20
LoL Champion Vladimir Build Guide
LoL Champion Vladimir Build Guide

Elite500, UNDISPUTED #1 VLAD PATCH 25.17

Guide by Elite500 updated September 8, 2025
  • In-depth
9.8
832
Votes
54
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.17] Twisted Fate guide - Grandmaster, Halfhand 🥇

Guide by Halfhand updated August 28, 2025
  • In-depth
9.7
180
Votes
15
LoL Champion Annie Build Guide
LoL Champion Annie Build Guide

[15.17] Rank 1 Annie Complete Guide | By Coach xblademojo

Guide by xblademojo updated August 27, 2025
  • In-depth
9.5
591
Votes
36
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

💀[NEW SEASON 16] CASSIOPEIA - The POISON Queen of Midlane ☠ 💀

Guide by RezoneVerified updated September 8, 2025
  • In-depth
9.5
990
Votes
77
LoL Champion Kassadin Build Guide
LoL Champion Kassadin Build Guide

[15.17] Rank 1 Kassadin Complete Guide | By Coach xblademojo

Guide by xblademojo updated August 27, 2025
  • In-depth
9.5
355
Votes
30
LoL Champion Malzahar Build Guide
LoL Champion Malzahar Build Guide

[15.17] Rank 1 Malzahar Complete Guide | By Coach xblademojo

Guide by xblademojo updated August 27, 2025
  • In-depth
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AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYunaraYuumiZacZedZeriZiggsZileanZoeZyra
Teamfight Tactics Guide