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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 2 Guides // Patch 25.15
6.7
17
Votes
10
LoL Champion Yone Build Guide
LoL Champion Yone Build Guide

[Season 14] Sakuritou Challenger Yone Guide

Guide by Sakuritou updated July 31, 2025
New Guide
LoL Champion Vladimir Build Guide
LoL Champion Vladimir Build Guide

Master Vlad Guide

Guide by Guest updated July 31, 2025
5.1
12
Votes
15
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[Season 14] Sakuritou Challenger Katarina Guide

Guide by Sakuritou updated July 31, 2025
2025, Season 2 Guides // Other Patches
10
132
Votes
3
LoL Champion Azir Build Guide
LoL Champion Azir Build Guide

The Most In-Depth Azir Guide Ever

Guide by Divine Azir updated July 23, 2025
  • In-depth
10
242
Votes
48
LoL Champion Diana Build Guide
LoL Champion Diana Build Guide

#1 Diana SEASON 15 MID GUIDE!

Guide by Xalt updated July 19, 2025
  • In-depth
9.8
42
Votes
1
LoL Champion Syndra Build Guide
LoL Champion Syndra Build Guide

✔️ How to throw Balls

Guide by Fruxo updated July 25, 2025
  • In-depth
9.8
277
Votes
4
LoL Champion Ahri Build Guide
LoL Champion Ahri Build Guide

✔️ How to use Charm

Guide by Fruxo updated July 25, 2025
  • In-depth
9.8
489
Votes
35
LoL Champion Lissandra Build Guide
LoL Champion Lissandra Build Guide

🍦 [ 25.14 - SEASON 15 - The MIDLANE ICE QUEEN OF DEATH! 🍦

Guide by RezoneVerified updated July 18, 2025
  • In-depth
9.7
177
Votes
15
LoL Champion Annie Build Guide
LoL Champion Annie Build Guide

[15.5] Rank 1 Annie Complete Guide | By Coach xblademojo

Guide by xblademojo updated July 30, 2025
  • In-depth
9.7
20
Votes
0
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.14] Victorious Twisted Fate Guide for Season 15 | Jammed

Guide by Jammed updated July 17, 2025
  • In-depth
9.5
350
Votes
29
LoL Champion Malzahar Build Guide
LoL Champion Malzahar Build Guide

[15.5] Rank 1 Malzahar Complete Guide | By Coach xblademojo

Guide by xblademojo updated July 30, 2025
  • In-depth
9.5
983
Votes
77
LoL Champion Kassadin Build Guide
LoL Champion Kassadin Build Guide

[15.15] Rank 1 Kassadin Complete Guide | By Coach xblademojo

Guide by xblademojo updated July 30, 2025
  • In-depth
9.5
62
Votes
3
LoL Champion Irelia Build Guide
LoL Champion Irelia Build Guide

Blade Dancer Guide Top/Mid (FOR BEGINNERS)

Guide by xumi_k updated July 28, 2025
  • In-depth
9.5
365
Votes
13
LoL Champion Kayle Build Guide
LoL Champion Kayle Build Guide

Rank 1 EUNE Top 8 EUW I Season 15 Kayle Guide by DesperateNasus Multi-Season Challenger

Guide by Desperate Nasus updated July 16, 2025
  • In-depth
  • Stream
9.4
113
Votes
14
LoL Champion Talon Build Guide
LoL Champion Talon Build Guide

[25.14] OTP Master Talon Guide with All combos / Season 15

Guide by AmiGo1v9 updated July 16, 2025
9.2
2693
Votes
168
LoL Champion Heimerdinger Build Guide
LoL Champion Heimerdinger Build Guide

🔧[ 25.14 MASTER TIER 10 MILLION MASTERY HEIMERDINGER 🔧 SEASON 15 ]

Guide by RezoneVerified updated July 24, 2025
  • In-depth
9.2
1982
Votes
128
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.13] Nyro Challenger Katarina Build Guide

Guide by Nyrolol updated July 21, 2025
9.2
56
Votes
5
LoL Champion Diana Build Guide
LoL Champion Diana Build Guide

[25.14] [Live] Best Midlane Diana Guide - Diimoonz -

Guide by Diimoonz updated July 19, 2025
8.9
19
Votes
2
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[15.15] Katarina AD

Guide by KingGamer1505 updated July 23, 2025
8.9
178
Votes
33
LoL Champion Zed Build Guide
LoL Champion Zed Build Guide

Zed Guide [S15]

Guide by Balinthun873 updated July 25, 2025
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AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYunaraYuumiZacZedZeriZiggsZileanZoeZyra
Teamfight Tactics Guide