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Q > E max - overall you should go Q->W->E
0/15/15 masteries are pretty sucky (especially the way you spec'd them)
Runes are poor, just do the math on flat health seals + armor quints vs flat armor seals + health quints. You'll quickly find out that health seals and armor quints are clearly a better choice. Also I'm sure there are better options than armor marks.
Items are decent though, but I'd still remove zeke's and thornmail as they aren't as well fit on thresh considering the alternatives. Mikaels could be moved to situational as the stats don't really benefit thresh (you should only get it if your team really needs it anti cc)
But like i said this is my first full guide and i'm still trying tho learn this.
Besides, maxing Q or E until level 9 is the best kind of skill sequence.