So I decided to make my own build for Twisted Fate, since he's become my main character over the last few weeks. This build focuses on a very balanced offensive attack, with plenty of crit. chance, lifesteal, and attack speed/damage.

The runes focus on some extra crit. chance, and very important armor penetration. The armor penetration helps early game farming. My masteries are a standard 21-0-9 with a point in greed, to help pay for some of the expensive items, and since TF isn't very mana hungry.

I like to start out with a Dagger and a health potion, but you can also start with a Doran's blade, or Boots and 3 Health Potions. I think Starks Fervor is an amazing early game item, giving 40% attack speed, 20 armor reduction, and 20 lifesteal - Exactly what we're looking for. Great aura for the team also. Bloodthirster gives that extra damage, and if you kill some minions, you will have ridiculous lifesteal mid-game. When you get your Bloodthirster you will be able to solo most champs pretty easily. Get Black Cleaver next, and with all this Armor penetration, tanks will be no problem at all. Next get your IE then your PD. Obviously this build is subject to change. ALL BUILDS SHOULD BE USED AS GUIDELINES!! You are not obligated to follow a build EXACTLY. Change it up depending on what the other team is doing! That's what this game is all about! Good luck and have fun!