At start you spam voley as you please...when you reached lvl 6 you just push D and voila...full mana and u can use ulti ...i never had mana problems on her.The AP masteries for the ulti is perfect for low hp / armor champions on mid such as twitch :)

Couple concerns here, hoping you can clear it up for me.

You took Archmage's Savvy and Archaic Knowledge, but you skipped over Sunder. Why? Ashe's only ability that does magic damage is her ult, so these only benefit that ability. Armor penetration benefits her auto attacks and volley though. Can you clear this up for me?

Also, how do you manage your mana at the start if you start with a Vampiric Scepter? You have no mana regeneration runes or masteries listed, so you must run out of mana incredibly fast.