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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 2 Guides
9.8
1307
Votes
52
LoL Champion Akali Build Guide
LoL Champion Akali Build Guide

[25.16] The Ultimate Guide to Akali the Rogue Assassin

Guide by iwontdominatelol updated August 25, 2025
  • In-depth
9.8
360
Votes
22
LoL Champion Rumble Build Guide
LoL Champion Rumble Build Guide

[14.24] Through the Fire & the Flames v4.4.0 - OUTDATED DUE TO CHRONIC ILLNESS; Next update unknown

Guide by Xelikari updated August 24, 2025
  • In-depth
9.8
45
Votes
1
LoL Champion Syndra Build Guide
LoL Champion Syndra Build Guide

✔️ How to throw Balls

Guide by Fruxo updated August 15, 2025
  • In-depth
9.8
371
Votes
49
LoL Champion Sylas Build Guide
LoL Champion Sylas Build Guide

[25.16]✨ OTP Sylas MID Guide

Guide by angeLoon updated August 14, 2025
9.5
590
Votes
36
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

💀[NEW SEASON 15] CASSIOPEIA - The POISON Queen of Midlane ☠ 💀

Guide by RezoneVerified updated August 25, 2025
  • In-depth
9.5
75
Votes
10
LoL Champion Nasus Build Guide
LoL Champion Nasus Build Guide

[25.16] Best Nasus Mid EU - Simplest In-Depth Guide S2025

Guide by SurferKiller updated August 24, 2025
  • In-depth
9.5
1985
Votes
128
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.16] Nyro Challenger Katarina Build Guide

Guide by Nyrolol updated August 22, 2025
9.5
2695
Votes
168
LoL Champion Heimerdinger Build Guide
LoL Champion Heimerdinger Build Guide

🔧[ 25.16 MASTER TIER 10 MILLION MASTERY HEIMERDINGER 🔧 SEASON 15 ]

Guide by RezoneVerified updated August 18, 2025
  • In-depth
9.5
491
Votes
36
LoL Champion Lissandra Build Guide
LoL Champion Lissandra Build Guide

🍦 [ 25.16 - SEASON 15 - The MIDLANE ICE QUEEN OF DEATH! 🍦

Guide by RezoneVerified updated August 14, 2025
  • In-depth
9.1
115
Votes
15
LoL Champion Talon Build Guide
LoL Champion Talon Build Guide

[25.17] OTP Master Talon Guide with All combos / Season 15

Guide by AmiGo1v9 updated August 26, 2025
8.9
870
Votes
50
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

❤ 🎶 [SEASON 15 NEW - 25.16 ] MASTER MID Seraphine! SEASON - THE SONG OF DEATH 🎶🎤

Guide by RezoneVerified updated August 25, 2025
  • In-depth
8.9
165
Votes
19
LoL Champion Veigar Build Guide
LoL Champion Veigar Build Guide

Veigar - Carry Alone

Guide by ReapeRGP updated August 22, 2025
8.9
185
Votes
35
LoL Champion Zed Build Guide
LoL Champion Zed Build Guide

Zed Guide [S15]

Guide by Balinthun873 updated August 17, 2025
8.6
482
Votes
39
LoL Champion Orianna Build Guide
LoL Champion Orianna Build Guide

⚡ [SEASON 15 UPDATED!! ] Master Tier Midlane Orianna! THE BALLS HURT ⚡

Guide by RezoneVerified updated August 18, 2025
  • In-depth
8.6
535
Votes
70
LoL Champion Swain Build Guide
LoL Champion Swain Build Guide

[ Patch 25.16 NEW SEASON 15 UPDATED!! ] - SWAIN is the GOD OF MIDLANE PAIN! - 🤯

Guide by RezoneVerified updated August 18, 2025
  • In-depth
8.3
650
Votes
54
LoL Champion Anivia Build Guide
LoL Champion Anivia Build Guide

👉 🧊[ NEW SEASON 15 ] - Master's Guide to Midlane ANIVIA! S TIER PICK! 🧊 👈

Guide by RezoneVerified updated August 18, 2025
  • In-depth
8
124
Votes
22
LoL Champion Aurora Build Guide
LoL Champion Aurora Build Guide

[ AURORA MIDLANE GUIDE SEASON 15 - 25.16 🐰[AURORA IS THE MOST ANNOYING MIDLANER 2025]

Guide by RezoneVerified updated August 18, 2025
  • In-depth
7.8
12
Votes
3
LoL Champion Neeko Build Guide
LoL Champion Neeko Build Guide

HOW TO BE IRL CAMELEON ── .✦!! 🦎✨ FULL SUPP/MID GUIDE

Guide by neekogf updated August 15, 2025
  • In-depth
7.7
510
Votes
57
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.16] Incursios' Challenger Item Quick Guide to Dominating Mid

Guide by IncursioOCE updated August 15, 2025
7.5
6
Votes
1
LoL Champion Tristana Build Guide
LoL Champion Tristana Build Guide

🔥FIRE AT WILL🔥 - How to Dominate ARAM as Tristana

Guide by GuessImHereNow updated August 20, 2025
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AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYunaraYuumiZacZedZeriZiggsZileanZoeZyra
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