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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 2 Guides // Patch 25.12
9.5
165
Votes
8
LoL Champion Akali Build Guide
LoL Champion Akali Build Guide

Anguishs GrandMasters Akali Mid/Top S15 Guide Patch [15.12] - Every Matchup/Item/Rune explained!

Guide by Anguish333 updated June 16, 2025
  • In-depth
9.5
190
Votes
17
LoL Champion Zoe Build Guide
LoL Champion Zoe Build Guide

[25.12] clipbot's Zoe guide for beginners

Guide by Aegox updated June 12, 2025
  • In-depth
9.2
410
Votes
43
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

(25.11) Eriosun's Complete Master Katarina Guide - Season 15 [UPDATED]

Guide by Eriosunx updated June 12, 2025
  • In-depth
9.2
1981
Votes
128
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.12] Nyro Challenger Katarina Build Guide

Guide by Nyrolol updated June 12, 2025
  • Stream
8.9
266
Votes
47
LoL Champion Ekko Build Guide
LoL Champion Ekko Build Guide

Power leon's guide for ekko players in mid lane

Guide by leonidas44 updated June 21, 2025
8.9
91
Votes
11
LoL Champion Qiyana Build Guide
LoL Champion Qiyana Build Guide

(25.11) Eriosun's Qiyana Midlane Master Tier Guide, Rank 1 on the 24 Sisters - Season 15 [UPDATED]

Guide by Eriosunx updated June 12, 2025
  • In-depth
8.9
602
Votes
35
LoL Champion Azir Build Guide
LoL Champion Azir Build Guide

[Season 15] BodyThoseFools' Challenger Azir Guide [In-depth] (10,000,000+ Mastery Points) (Beat Faker)

Guide by Body Those Fools updated June 11, 2025
  • In-depth
8.6
162
Votes
19
LoL Champion Veigar Build Guide
LoL Champion Veigar Build Guide

Veigar - Carry Alone

Guide by ReapeRGP updated June 24, 2025
8.3
16
Votes
3
LoL Champion Vladimir Build Guide
LoL Champion Vladimir Build Guide

Vlad 15.10+ Item Guide

Guide by KormitLeFrag updated June 20, 2025
8.3
503
Votes
46
LoL Champion Akali Build Guide
LoL Champion Akali Build Guide

(25.11) Eriosun's Complete Master Akali Mid-Top Guide - Season 15 [UPDATED]

Guide by Eriosunx updated June 12, 2025
  • In-depth
7.9
10
Votes
2
LoL Champion Neeko Build Guide
LoL Champion Neeko Build Guide

HOW TO BE IRL CAMELEON ── .✦!! 🦎✨ SUPP/MID GUIDE

Guide by neekogf updated June 23, 2025
  • In-depth
7.4
19
Votes
8
LoL Champion Irelia Build Guide
LoL Champion Irelia Build Guide

[25.12] AP Irelia Ultimate Guide

Guide by SkandalloTV updated June 21, 2025
  • In-depth
  • Off-Meta
7.3
83
Votes
27
LoL Champion Zeri Build Guide
LoL Champion Zeri Build Guide

[25.12-Buff] ⚡️Get Zapped⚡️Zeri Ap Oneshot Build

Guide by Bambado updated June 13, 2025
7.2
6
Votes
2
LoL Champion Ezreal Build Guide
LoL Champion Ezreal Build Guide

A G̶l̶o̶r̶i̶o̶u̶s̶ Magnificent Guide To AP Ezreal (dont strike me Darkk mane)

Guide by KarateciKagan updated June 16, 2025
  • Off-Meta
6.8
112
Votes
24
LoL Champion Yasuo Build Guide
LoL Champion Yasuo Build Guide

(25.11) Eriosun's Master Midlane YASUO Guide Season 15

Guide by Eriosunx updated June 12, 2025
  • In-depth
Rating Pending
LoL Champion Anivia Build Guide
LoL Champion Anivia Build Guide

(Phoenix Approved) Anivia - Frozen Ashes

Guide by Kyle007 updated June 11, 2025
  • In-depth
Rating Pending
LoL Champion Naafiri Build Guide
LoL Champion Naafiri Build Guide

(Phoenix Approved) Naafiri MID - The Pack Survives

Guide by Kyle007 updated June 12, 2025
  • In-depth
Rating Pending
LoL Champion Kassadin Build Guide
LoL Champion Kassadin Build Guide

PIPOTAM ELO GUIDE

Guide by VYPRCXDD updated June 16, 2025
  • In-depth
Rating Pending
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.12] Twisted Fate Guide - Emerald

Guide by GamblingAddict updated June 12, 2025
2025, Season 2 Guides // Other Patches
9.9
145
Votes
64
LoL Champion Heimerdinger Build Guide
LoL Champion Heimerdinger Build Guide

[25.11] In-Depth Heimerdinger Guide [Mid/Top/Bot/Support]

Guide by SanyGame updated June 6, 2025
  • In-depth
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AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYuumiZacZedZeriZiggsZileanZoeZyra
Teamfight Tactics Guide