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If you want AP, don't build Nashor's Tooth.
I want AP, attack speed and CDR, that's why I chose Nashoor's. I can't heal from Wit's End's procs and 25% faster exoskeleton can really help you get where you're needed or survive longer. This is a hybrid build, otherwise I would have chosen other options like the ones you listed.
There are a total of 0 champions in the game i would build Nashor's Tooth on.
If you want CDR, build shurelya's, if you want AtS build Wit's End.
If you want AP, don't build Nashor's Tooth.