Malphite

Malphite is the BIGGEST Vayne counter. Its really hard to play against it and you struggle a lot. Recommend to ban malphite in 99.9% of the games. Doesnt matter if he plays ap or tank he is still super strong and u have 20% of winning the lane (depends on your, his playstyle). If you play against malph take the first build with the first runes. Play it safe and try to do as much dmg as possible.Ask for jg help or try to kill him at least once if its possible if its not then just play it safe and farm till you scale and you are strong ( try not to die). If you kill him once or twice without dying THEN you are at a very good position and you have high chances of winning lanephase and game! Your main focus, Goals should be DMG to malphite, Higher cs, Maybe 1-2 roams and if you are lucky enough 1-2 kills.

Quinn

Quinn is really strong against vayne and extremely hard but not harder than malphite. Against quinn i recommend to take flash ignite 1st build and 2nd runes! Your goal is to focus on cs go lvl2 first and try to kill her early if you achieve that then let her roam with her ult and keep focusing on cs. outscale and win! Dont forget to play safe early because she is really strong!

Teemo

Teemo is only hard against because of his q. All you can do is take 2nd runes 1st build and flash ignite. Bait him for him to q you and when he waste his q Press your ulti and q to become invisible and then just start attacking + apply him ignite and easy kill! (Take oracl for mushrooms)

Varus

Varus is strong early game you really dont have chance against him if he is good. If you can maybe dodge qs and es maybe but if you cant then dont even try! Take flash ignite first build and first runes! Play safe farm try to do dmg and when you get the chance roam or kill him!

Nasus

For Nasus play early game focus on him he is very weak. focus on dmg and kills. If you are not above him late game then i am sorry but you lost the game and laningphase. All you have to do is to be really aggressive do as much dmg as possible and just be above him on cs,xp,gold etc... Dont let him stack you need good wave management here! when you are really above try to do solo kill and go roam and help team!

Sion

Sion is not hard focus on dmg and gold. Dodge his q with your e or q and do dmg. Try to solo kill early because late game he will outscale you

Gnar

Easiest matchup ever Just play for dmg early and dodge his q's try to kill and anoy him!

Sett