My Englist is bad, I hope you forgive me.

8% of HP is huge, for any champion. So this build is based on silver bolts and we will try to obtain near 2.5 attack per second and have a maximum survivability.

Of course, adapt this build to the circumstances.

Pros :
-Tank killer. (R.I.P Mordekaiser)
-Heavy damage and good survivability in late game.
-Good escape and gank ability with condemn and tumble
-Versatile ult. Good for hunting and hiding in teamfight.

Cons :
-Low damage at start.
-Weak against CC team.
-Expensive stuff.

Mark : We have silver bolts level 5 quickly. Having the best attack speed the sooner as possible is important.

Seal : Improve your survivability. Take HP per level if you take the mid lane. Take HP or evasion on other lane.

Glyph : Magic res ! You don't need anything else here.

Quintessence : I like quintessence of switness. It goes well with boots and passive at start. If you don't like this, take HP or attack speed.

Ghost, tank, attack speed. Nothing to say more.

You don't need cooldown reduction or mana. You don't play with critical or your AD in this build.

They have so many way to build vayne. And it depends on what you have in the other team or if you take the mid lane.

I take boots because i like to play mid lane and i can't harrass corectly without. Having 3 potion will make a difference against doran's ring or item's combo with only one potion.

If you are not going mid lane, a doran shield should be a good idea, but boots + 3 potions is good enough. Juste don't harrass too far of your tower, you will lose your fight against other ranged champion before having your ult and a decent attack speed.

Berserker's greave at start ! Rush as many attack speed as possible ! If they have CC, change your boots for mercury's thread in mid game.

Zeal and two recurve bow, if a champion have a good dodge, buy a sword of the divine. The + 30 armor penetration active skill suit good with your ult.

After this, you do insane damage with your auto attack. Go for suvivability. I like the bloodthirster, it allow you to regen after a fight and having +100 damage make you a good anticarry.

Warmog's armor, nothing to say. Just buy it ! You will be focus and banshee won't be enough ....

Madred's Bloodrazor, Trinity force if the game isn't finished.

Ghost : You will have to follow your target and creep will slow you down. Running or join a teamfight quickly.

Flash : Your passive, ghost, tumble, your ult. If a target don't die, juste blame yourself. Will save your *** many time.

Exhaust : You don't have a slow in this buid before Trinity force. But you can do without, you are vayne. No, you have to learn to do without !

Teleportation : For gank.

Sorry for my poor english. Feel free to correct me.