Honestly I leave all the time in the middle of the game to get a Redbull or a cup of coffee. But I play Mordekaiser so it doesn't even matter. You can miss like 10 minutes of the game, but Morde is so strong you can come back and still 1 shot people, even fully built tanks. So I'd recommend picking him up, because that's how you win ranked games. Your team might rage at you for leaving, even though you'll carry, so just mute and report them immediately at the start of the game.
If you want you can check out my Mordekaiser Guide Once a month I update it daily.
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I can't anticipate every match will be completely open. I do my best to play during times I wont be bothered but planning your life around a videogame isn't that easy. Part of why I stick to playing normals versus ranked usually.
Just wondering how Riot deals with the occasional leave.