Marks is pretty much your choice. Depending on the champion, you should get either MPen or ArPen (shen and amumu would get MPen, rammus would get ArPen).
Seals can be either dodge or armor (dodge might work against a champion like amumu, who gets a benefit from being hit - his cooldown on
Tantrum is reduced).
MR would be best for blues, but if you have a mana-thirsty champion you want to play (malphite, for instance), then mana seals might be nice (though you could just get mana per 5 seals instead).
Quints would be anything you want - flat health is the best universal choice, but there's seals for everything.
Seals can be either dodge or armor (dodge might work against a champion like amumu, who gets a benefit from being hit - his cooldown on
Tantrum is reduced).MR would be best for blues, but if you have a mana-thirsty champion you want to play (malphite, for instance), then mana seals might be nice (though you could just get mana per 5 seals instead).
Quints would be anything you want - flat health is the best universal choice, but there's seals for everything.
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Trojan and Jebus are absolutely right. If you have more questions about runes I'd suggest using this resource: http://www.mobafire.com/league-of-legends/build/rune-tips-what-secondary-and-primary-means-and-more-24255
Simplejack5
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Dodge seals all the way on all tanks you get the dodge masteries on.
"I'm ebolakin. You can refer to me as Ebola-Chan." - Vurtax
"I also am Otherkin. Whenever autumn rolls around I can feel my kin-type slowly taking over my body. You must know, I identify as pumpkin. I can control it pretty good most of the time, but when September ends, I just cant hold it in anymore. Whenever Im outside I see my brothers and sisters being chopped into soup, coffee, donuts, cake, drinks, bread - ppl even cut human faces into their skin, making a mockery out of their noble appearance. When I see things like that I cant control my pumpkin urges anymore. My natural instincts kick in. I then sit down motionless, while getting bright orange." - Morgana L
"I also am Otherkin. Whenever autumn rolls around I can feel my kin-type slowly taking over my body. You must know, I identify as pumpkin. I can control it pretty good most of the time, but when September ends, I just cant hold it in anymore. Whenever Im outside I see my brothers and sisters being chopped into soup, coffee, donuts, cake, drinks, bread - ppl even cut human faces into their skin, making a mockery out of their noble appearance. When I see things like that I cant control my pumpkin urges anymore. My natural instincts kick in. I then sit down motionless, while getting bright orange." - Morgana L
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