While I like some aspects of your build I made a few changes of my own, feel free to try them out.

#1 I like to start with Doran's Blade. The little lifesteal can help lane longer, the extra attack damage is nice, but most importantly the HP help a lot until the end game.

#2 Next I get berserk's greaves... her passive is not enough to make up for not having boots for so long, especially if you need to run AWAY from a gank.

#3 I'm not a fan of the Stinger idea... there are better AS items for Vayne, as the CDR is not very important with a 2 second Q and a passive ability. With this in mind, even if you are not going strait for Trinity Force I still think a sheen at this point is an excelent buy -- how can you deny double damage after every roll?!

#4 Next I went for Sword of the Divine -- excellent choice with the massive AS and procs on top of her passive.

After that I go for Black Cleaver then my Trinity Force... Madred's seems like overkill, you already have a ton of AS and passive magic damage, better off getting some more survivability like a Banshee's in the middle if needed.

Just my 2 cents.

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Yes i realized the Last whisper was a poor choice, this has been changed.

not only that but do you realize how fast you hit the trinity force anyways? because everything before it was so cheap.

The cost efficiency is terrible. 4k for a little AS? I can hit 100 percent AS with only 2.5k items.

to late trinity force its very good item for vayne

It's quite a good guide. With everyone following the spotlight and no one attempting other things it's nice to see an idea that I had thought of for her. I have some thoughts about your build and would like to hear your reply. But this is one of the first guides I've seen that has tickled my fancy.

1.I do like the fact you get a Stinger, and a Sword of the divine, but Why build Berserker's Greaves if you are already have a lot of attack speed. Wouldn't Speed Boots help? (I realize her passive gives her Movement speed but wouldn't extra speed while you're Not attacking, helping running or dodging skill shots help. Or even Mobility boots if you roam after level 6, making you very fast at switching lanes.)

2.Why that skill build? You haven't really explain it. While it does look like you level everything at a steady rate, if you're going Stinger then SotD and even AS boots, wouldn't you want your Silver bolts to be as High as possible if you lack AD at the start?

3.I see your reason for both SotD and Stinger, but getting a lot of attack speed with no damage could hurt you, plus the 100 true damage from SotD would be slightly wasted as tanks, by the time you reach SotD would Just start getting their items, and usually it focuses on either AD or AP depending on whats hurting them, (Usually AP > AD for starters) So you might want to think about maybe rushing up that Phage before hand, it would give you a chance to slow and some more HP, for quite a low price, and it would also allow you to hit More times.

Those are just some slight questions that came to mind when I saw your build. 2 Problems I have are the fact you start with a Attack speed dagger and Last whisper, In ranked play, or even high level pub play. (<- because this totally exists) Unless you have a very easy lane not having any form of healing could hurt, Maybe cloth armor and 5 pots could be a suggestion to start with, you have attack speed runes for the start Plus it also builds into your madreds which you get later. And last whisper seems out of place in the build, You could forgo the theme of the build and change it for something that has attack speed, or Drop it and build some survivability, like a Banshee's for example. Because with the little attack damage you do get, having 40% pen wouldn't do much if most of your shots are true damage.

My 2 cents, Hope to hear back.

Yes. I have been editing, i posted very similar builds that were only slightly different. As i have said in the guide though; ghost is used for running away. I will also give flash as an option, since sometimes I use this too. As with any build, some things can be interchangeable.

Only one build visible, might want to check that out or remove your 'GO WITH BUILD TWO' references.

Also, if "ANY MORE SPEED IS A WASTE DONT LISTEN TO THE OTHER GUIDES." then why did you get ghost?

You also forget to mention that the speed boost is only when playing offensively, as soon as you try do go def you loose your speed boost, and have extremely limited use of your tumble unless you can find something to hit after each roll.