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Here's some constructive criticism.
1) Your runes are mostly fine. I'm concerned about the Marks of Strength and Seals of Evasion though. There are better runes out there for Nasus.
2) While I can see that you're interested in Nasus' mana problems,
3) You should build up resistances (such as armour and magic resist) before you build warmog's armour.
4) You have more than 6 final items in your Purchase Order.
5)
6) Your Mastery Tree is... unique. There's a reason why no one goes 0/25/5 - because it's a tad silly. If you want defense, and utility go 0/15/15. Or 0/21/9.
7) "Manamune gives Nasus the ability to have an almost unlimited amount of mana so he can spam his abilities." The problem with this statement is that you buy no cooldown reduction items, so Nasus can't spam his abilities as much as you claim. Without
8) "Since I dont typically go for Ninja tabi in sacrafice for more tencaity against all CC and the starting magic resist the dodge runes are a must because any well built enemy team SHOULD have melee heroes and a dodge is the best defense since a dodge means no damage at all." This is not a good reason to specify in dodge runes and dodge mastery points. Unless you can dodge like a boss (ie
9) "Instead buff your spirit fire since AP is never used on Nasus thus spirit fire gets no boosts other than its levels." This is not a good reason to level up
10) I don't mind
I would also recommend turing on "comment to vote" so that the people who downvote are commenting to give you their reasons for doing so.
Goodluck ^^
- jhoijhoi
But come on.
And you're Nasus no need for Guardian
2. you get a manamune without getting frozen heart
3. you get a warmog's.
4. you don't get a trinity force.