I like Karthus more because if you stick him in mid he can still play a larger role in the game with his Ult by not even risking himself with death. Talon has to be fed up top I believe to be a huge threat to the game.
Talon is a great low Elo stomper. He can deal with any lane pretty good if you can play him right. He instagibs squish targets. He's just all-around fun.
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Karthus if you like the sound of enemies going "Noob ulti QQ" hehe \o/

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Talon if you wanna win everygame low elo and Karthus if you like to deal massive burst and then die and **** them all up with your ulti.
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