I wanted to just show you guys the battle I just battled with my friends. It was very tough fought and very challenging. It was as a custom battle obviusly. I was Vladimir and kicked butt.
So I just want to tell you how it went.

The runes I used were mostly mana stuff I did that because I thought about how he has so much health I decided to boost up his mana so I can use Vlad's Spells more often but not to much because his spells cost health but I wanted the mana just if i need them badly. My second choice would have been health for him because even if you have mana for the spells you might not have the health for them. Now my friend that was Kennen (jayden101) chose his runes because he wanted more energy for energy strike and all his other spells he also got magic penetration, mana regen, and so cooldowns are faster. My other friends that were Nasus and Teemo i have no idea why they used thier runes.

I dont remember why.

I bought my items because again i needed mana or health and some attack but not much.