This is my first guide, the reason I'm making this simple guide is because I couldn't find much guides on Elise online right now, so I thought I should just make my own. :)

Elise is an awesome spider and some may say that is an AP bruiser. I will be just telling the basics, so if you're looking for a really simple guide, you have come to the right place, but if you're looking for a comprehensive guide, you're going to have to wait for more experienced guide-makers and LoL players to make one. XD

Items

Other than the items I have listed above, you can also consider the following:

Abyssal Mask:

It's magic resist and magic resist reduction works great on Elise, due to her melee spells while she's in spider form.

Haunting Guise:

This is a great item to make her more tanky and more like an AP bruiser. It also provides a nice 20% magic pen.

Skills

Neurotoxin / Venomous Bite:

Use Neurotoxin when the enemy's health is high and use Venomous Bite when their health is low.

Needless to say, start off using Elise in her human form and finish them off with your spider form.

Spider Form / Human Form:

Always remember that Spider form gives you a boost to your magic resist, armor, magic damage, and movement speed.

This makes Elise more tanky and also helps her get back to lane faster.