Zao San, I'm Hotshot GG from Counter-Logic Gaming and I'll be teaching you how to play Brand. Brand is one hell of a nasty slayer. His ulti has gotten me many plays on ProtatoMonsters' Top 5 plays. Overall, one of the best mids in the game.

Runes are purely your choice but I would suggest full ap runes.

21/0/9. Nothing else.

Start off with boots and 3 health potions for the sustain. Get 2 Doran's Rings for more sustain and then immediately rush a Rylai's Crystal Scepter. Take Sorcerer's Shoes whenever necessary and then build a Rabadon's Deathcap. The next few items a situational, ranging from a Void Staff to a Maw of Malmortius. Now, you'll probably ask me why Maw of Malmortius? Well, Brand is a great ad champion as well, his combo with a few auto attacks will severly damage any champion.

Flash + Ignite will probably be the best but you can also get smite. Brand has solid ganks and will easily carry you to victory.

In ranked play, always play Brand as a jungler. It's the most solid and consistent playstyle for Brand.

Pros: Good Burst, Large amount of Health, CC, Easy Pentakills.
Cons: No cons, just overpowered.

Good Luck, hope my guide helped.