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Other than Vi's annoying ult, she can't do a lot to Nunu. Feel free to build a more AP Nunu against Vi, but be careful during team fights.
Rengar
Rengar isn't able to deal enough damage. Hit him with your E, W yourself, then auto attack him to death.
Evelynn
Evelynn is very speedy, and her stealth can be annoying. Stay away from Evelynn. If you can hit her with your E, then ult during team fights, it's lights out. Otherwise, stay away from her.
Elise
Elise can be annoying with her healing W in spider form, and she can easily match your tankiness during fights. Make sure you have the mana, and your abilities if you come toe-to-toe with Elise.
Lee Sin
Lee Sin is pretty much a push over throughout the game. Early game, he can definitely bully with more damage than you, but poking him with E at any chance you can will keep him in check.
Jarvan IV
Jarvan can be tanky, but building a little AP will take care of him.
Nocturne
Nocturne is pretty even to Nunu. Watch our for his ult. If you can keep him from using his ult, and you can get some good combos, you can take him out.
Master Yi
Master Yi is annoying, and he will have the attack speed over you. Make sure to build some tank against him and you can E him all day.
Amumu
Amumu is pretty even to Nunu. His ult can really mess you up, so try to avoid getting caught by his ult in team fights, and hit him with an E during team fights and use ult while he is right next to you for greater damage.
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