When i first saw Ezio was in LoL I got very exited because i really like him...So I made up a build for him and i think it's really cool. Enjoy it.!.!.

I pick AS runes because Ezio's an assassin and you want to kill people as fast as you can.
I also pick MR and Armor runes because Ezio,like all the assassins die pretty easy and you want that sustain in the laning phase (0-15 min) of the match.
I'd like to say that both AD and AS Quints are really good for Ezio.So pick whatever you want.

I pick 24/6/0...
with a little AD, CDR, MR and Armor.
I pick AD because Ezio scales from AD,
CDR because your abilities have little CD so it's easier for you to spam them :)
MR and Armor for the same reason as the runes.

You start with Doran's Blade for the AD and the health.
then you continue with Ionian boots for the cooldown and some mana pots.
If you are solo top you sould consider buying A Vamp Scepter before Youmuu's for your lane sustain.
When you finish your Youmuu's Buy a BloodThirster and again some mana pots because with 34% CDR you'll be spamming your Q which will have a 3-second CoolDown.It would be viable to buy a

MANAMUNE!!!!!

for you to spam your Q ALL TEH WAYY!!
After that buy a Cleaver for the AD/AS and a Phantom for the AS and the Critical.
Then buy an Infinity to finish a build and to get easier crits with your Q

Good Choices:

Heal: for easy lane sustain.
Exhaust:for the 1v1 fights.
Flash:because everyone likes Flash :3.
Ignite:for the easier champion last-hitting.

Bad Choices:

Promote:Why would you???
CV:You aren't a Fuuckin support...
Surge:Noooooooo...Fuuck Noo

So... I hope you liked my Ezio's Build.
Sorry for my bad english.
I don't know what to say now...*embarasing*