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Why would you auto attack, when you can always Q? You don't build AP on Ryze, Lich Bane's passive does damage based on your ability power. You dont' have any. It does no damage.
Ryze's Q's CD refreshes after casting ANY spell, so there is no reason to auto attack when you can just Q.
CDR Glyphs > Magic Pen Glyphs tho.
+rep to you ;)
overload 10%
Frozen heart 20%
masteries 6%
then maybe get cdr glyphs?