So, I've always felt like twitch was a bad champion and a troll champion and you may have felt that too. So I tried him out and I really liked him and thought that he was fun to play! :D
And now I see twitch as a serious champion and just because he cannot 2 hit people anymore like he could before he was nerfed he is still one of the best ad carrys.
Don't believe me? try this full guide!

So twitch is now my favorite champion! But everytime I pick twitch in champ select in ranked everybody start to flame and call me troll pick, but then they see my incredible damage and they don't say a sh*t. Hope this guide can help you and if it did please vote up this guide! :D

Even though twitch got good attack speed skills he could use some extra on the way. That's why I take "Attack Speed Glyphs!"

If you want really good early game and mid game until you have gotten your last whisperer you should take "Armor pen Marks and Quints!" Atleast I strongly recommend it!

And at last twitch is probably the most squishiest champion in the game and that's why he needs "Armor Seals!"

So, these masteries boost twitchs damage even more! Just cross in the right masteries that I've crossed in at the top and you will be fine! :D

This guide is fully about carry twitch!
So this build have always worked for me!

Start with "Dorans Blade" and then rush "Berserkers Greaves" after that.
After that you should aim for the "B.F Sword" and if your doing good rush the "Infinity Edge" if your not doing so well buy a "Zeal".
Now you need your "Phantom Dancer"
Now you got much damage now we need some armor pen cause your enemies have probably started to build some armor at this point so here you take "Last Whisperer".
Now you need some defence, take a "Banshees Veil"
After that you can sell your "Dorans Blade" and buy a "Bloodthirster"
Just don't forget "Red and Green Elixirs".

This skill sequence aims for doing alot of damage with your passive and the "E" spell.
Also maxes "Q" after that to use your invisible ability that makes Twitch such a special ad carry!
Take the "W" at level 3 and dont max it until last levels!

If you follow this you should be good!

Like all other ad carrys take Exhaust and Flash!
But if there is alot of CC on the other team I recommend to take Cleanse and Flash or Cleanse and Exhaust!

Pros:
•High Risk High Reward Champion
•Highest attack speed among AD carries
•Stealth
•His E skill scales with AP which is an advantage early game (your enemy carry basically has to buy AD/AP defensive items)
•Can 1v1 anyone
•Strong Pusher
•Very good for solo Q
•Great Ganker
•Fun champion
•If well played your enemies will be scared to death


Cons:
•Hard to play the first times
•Squishiest champion in game
•Very risky
•Can be countered by oracle
•Low range
•No escape

This is a list from the best to the worst laning partners:

1. Alistar
2. Sona
3. Janna
4. Soraka
5. Taric

So, I hope this guide helped you and hope to see you guys use Twitch a little more in ranked! :D
Hope you guys make great success with this guide! Here is a picture where I hardcore carried in a ranked game :)