Build Guide by Builds for Pros
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Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
This build works only if you play more defensive than others in the start of the game. Make sure you never go first, check for Oracle Potions, and always try to harass like crazy in the lane baring phase. If you are going for a kill in a separate lane, make sure you use your abilities in this sequence. First, you must stealth and go behind your prey. Next, come out with Deliberating Poison, pop Spray and Prey, then once your opponent is below 3 bars of health left, expunge for the last hit. This can either be used for finishing the target off, or preventing kill steals. Also, always remember if your a killing someone in a lane that is not yours, make sure your partner can handle the lane for a while. If you choose the take the middle path, make sure that you harass like there is no tomorrow. But do remember to stay defensive, until you out level your opponent. Then, if you wish to do a stealth kill, go on ahead. But make sure you can kill them, because as Twitch, you are very squishy.
Easily takes away Oracle Potions
Fast turret killing
Hard fight close range
Seriously, don't get caught in turret
It is smart to harass many times. Stay at a distance for you are still very squishy. As long as you know they can't do much damage to you if you hit them, hit them a lot with normal attack harassment. Don't try to hard the First Blood them, because if you do, chances are, you will get first blooded yourself.
By now, you should have your Last Whisper. This will improve your harassment damage, and your level will improve your poison hits. At this point in the game, Ambush and Deliberating poison are very helpful. You should be ganking low health people, and stacking up gold. Best lane to gank would be top or bottom, for you can really get behind the prey. Your Deliberating Poison should be the source of most your kills, Along with exhaust for saving yourself against Master Yi, Sivir, Ashe, and mostly any DPS of this kind. It is especially helpful against Teemo because while you are blinded, guess what? He is too.
By now, if the other team doesn't have an Oracle Potion, they are dead ******ed. So most likely, they do. Be careful about going around people who have Oracle Potions, and tell your team to kill them first, main target. I like to phrase it like this, "Everybody target the ******* who got the Oracle, or just watch me feed. Cause that is what I will probably do with them seeing me. Yes Veigar, that includes you.'But I will die, I have no health' I don't give **** if your squishy, isn't that the tanks job? 'But...' JUST SHUT THE HELL UP AND KILL THE ******** ***** WITH THE ORACLE!"
That always seems to work for me.