Click to open network menu
Join or Log In
Mobafire logo

Join the leading League of Legends community. Create and share Champion Guides and Builds.

Create an MFN Account






Or

It's time for the 2025 Season 1 Guide Contest! Create or update guides during the following week to compete for the $3,750 prize pool. 🏆

LoL Best Vayne ADC Build Guides 2025

Build guides for Vayne ADC on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne ADC builds. Create your own champion guide!



Season 11 Builds
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

27,089,522K Million GOSU NEW HIDDEN ITEM GUIDE !

Build by Nawy updated November 14, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Magnum Explosion Vayne

Build by GabrielSanic updated November 13, 2020
  • Off-Meta
Season 10 Guides
8.3
10
Votes
1
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[10.22] In-Depth Vayne Build and Gameplay Guide

Guide by thelolbeast updated November 8, 2020
  • In-depth
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Ultimate Vayne Hard Carry Guide

Guide by Cam1304 updated October 30, 2020
7.7
11
Votes
3
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vibin with Vayne

Guide by PentasForDays updated July 16, 2020
7.7
11
Votes
3
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[ADC] Vayne Guide Patch 10.14

Guide by Twiggymocha updated July 13, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne-Kenshiro Hokuto late game w madness

Guide by Etrn updated June 28, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Guide | Build & Runes | 10.11 Patch [Updated]

Guide by Zoodyacc updated June 11, 2020
  • In-depth
9.5
28
Votes
2
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[S10.10] ADC Vayne, the Night Hunter - Lategame has Arrived

Guide by atonementblade updated May 13, 2020
  • In-depth
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne As Perfect As Udyr

Guide by Pingu Fugindo updated April 29, 2020
9.8
79
Votes
2
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Midorima's Vayne Guide (Patch 9.1) | THE SAUCE

Guide by Midorima updated March 20, 2020
  • In-depth
8
8
Votes
1
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

(Portuguese Guide) High elo Main Vayne guide Patch 9.24 (g

Guide by Falllol updated December 16, 2019
8.8
17
Votes
2
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Season 9 Vayne guide! Purge With Silver (9.23)

Guide by Laverenz updated November 27, 2019
  • In-depth
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne [The Night Hunter] Champion Guide

Guide by mhsmhs123 updated December 7, 2019
Season 10 Builds
7.8
7
Votes
1
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[NEW]AssassinVayne's Special Build

Build by LSCaspen updated October 18, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

ADC Vayne Guide Season 10

Build by Giuliano80 updated October 3, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

The NOOB's ARAM/SR Vayne Guide [Read Notes for SR]

Build by Crash1025 updated October 2, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

How to play vayne.

Build by hord_on_pc updated September 25, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne

Build by xSealed updated September 15, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne adc

Build by oOTrrixOo updated September 13, 2020

League of Legends Champions:

Teamfight Tactics Guide