LoL Best Vayne ADC Build Guides 2025
Build guides for Vayne ADC on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne ADC builds. Create your own champion guide!
Season 13 Guides
The Quintessential Vayne Guide: Walls, Rings, and Late Game
Reptile - EUW Challenger #1 Vayne ADC Guide (Patch 13.16)
Season 13 Builds
vayne
Vayne OffTank
Play Like ACE/ New School Vayne
[13.14] VAYNE ONE SHOT - SPAMMING Q
Vayne OTP build S13.8
AD CARRY - CAPTAINEVOX
[P12.23-S2022] BOTLANE ADC VAYNE CAPTAINEVOX
vayne
Will be updating Vayne Counters season 13 / Simple Vayne Build
Tank & AS Vayne
True Damage Vayne
Season 12 Guides