Best Vayne Build Guides 2025 for LoL Patch 25.S1.1

Rating Pending

Vayne
Build by Rosewhip92 updated April 2, 2024

Rating Pending

Vayne Guide
Build by NoZLXRD updated March 27, 2024

6.4

4
Votes
2

Vayne top [ S14 ] (only for people with no parents)
Build by HMT_zenith updated March 15, 2024

Rating Pending

Vayne
Build by GeneralHerc updated March 9, 2024

Rating Pending

(Master)-Vayne off tank / Mid-Late Game
Build by mix10 updated February 7, 2024

Rating Pending

Hyper Carry Vayne 1 Tabs
Build by WhisperOfEternity updated February 11, 2024

Rating Pending

Vayne Builds and Runes SEASON 14
Build by Tore updated January 18, 2024

Rating Pending

[14.2] Vayne - Full life Steal
Build by Chironex updated January 19, 2024

Rating Pending

[Season14] Vayne 1 Item Power Spike
Build by YKrow updated January 12, 2024

4.9

7
Votes
18

Master Vayne Guide 13.21
Guide by Trixiefix updated November 25, 2023

7

11
Votes
5

VAYNE TOP GUIDE 13.21
Guide by Tohru1273 updated November 3, 2023

9.5

3093
Votes
225

Season 13 - Vayne Guide - 13.20 Patch [Updated] [Ready]
Guide by Proxxii updated October 19, 2023

8.1

6
Votes
0

Season 13 ULTIMATE Vayne Guide. Every Build.
Guide by mythicdem0n updated September 4, 2023

Rating Pending

The Quintessential Vayne Guide: Walls, Rings, and Late Game
Guide by TheRealVayneGod updated September 2, 2023

8.3

119
Votes
20

Reptile - EUW Challenger #1 Vayne ADC Guide (Patch 13.16)
Guide by Reptile9LoL updated August 21, 2023

In-depth

Rating Pending

Vayne Support inspired by Woahokaybuddy
Guide by Fenreee updated August 26, 2023

Off-Meta

7.3

13
Votes
5

Vayne TOP/BOT [13.8] In-Depth Guide
Guide by ARCTIC33 updated April 29, 2023

In-depth

8.9

153
Votes
19

[13.7] BEST VAYNE TOP IN DEPTH GUIDE Detailed Match Up Sheet Included
Guide by SaskioLoL updated April 9, 2023

In-depth

7.5

12
Votes
4

Wait....Vayne has better scaling on Q than Draven?
Guide by memaybeo updated March 31, 2023