So searz I had a question: Since it's not goot to mix % pen and flat pen, what about for magic penetration? I know most people take the 15% mastery, as well as Mpen runes. Would it make sense to ditch the mastery and get sorcerer's shoes and haunting guise/abyssal for the flat pen, or take the mastery and get a void staff for the % pen? Wouldn't either choice be more effective than mixing both in any given game?
Miraisen - US

In ninjas we trust...
The mastery doesn't matter much. It's only if you're unsure about which marks to take. Like on Teemo. I take the MrP mastery on him so I go for AS marks instead of MrP.
The moment a religious person unknowingly calls his own ways stupid: "And lol. I highly doubt you have magic powers. If you proved it I would believe you, but since you 'refuse to', I choose not to."
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Last Whisper is a bad item on most AD champions. The Black Cleaver is far superior because it offers both Attack Damage and Attack Speed on top of ripping through a majority of a target's armor.
ONLY if you don't care about your physical abilities. Most champions with physical abilities are better off with LW.