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Vayne Build Guide for League of Legends

Champion guides for the League of Legends champion Vayne. Find the best Vayne build guides for S10 Patch 10.16. Our authors will teach you which items to build, runes to select, tips and tricks for how to how to play Vayne, and of course, win the game! MOBAFire shows the top rated guides per patch, but can also be sorted by other criteria such as all-time score, author rank, or newest guides. You can also find other League of Legends Champion Guides.

VayneThe Night Hunter

89% ADC More Details
Win
Rate
51%
Ban
Rate
12%
Pick
Rate
17%



Season 10 Guides
LoL Champion Vayne Build Guide

Vapora Dark In-Depth ADC Vayne Guide Season 10

Guide by Vapora Dark updated August 5, 2020
  • 10.16
  • In-depth
Votes: 1,698
Views: 8,981,632
LoL Champion Vayne Build Guide

Vayne: The On-Hit Abuser (Patch 10.16)

Guide by ifound1dollar updated August 5, 2020
  • 10.16
  • In-depth
Votes: 552
Views: 1,636,540
LoL Champion Vayne Build Guide

<Grandmaster> LostFish - Vayne: The Guide

Guide by LostFishEU updated August 9, 2020
  • 10.16
  • In-depth
Votes: 59
Views: 143,290
LoL Champion Vayne Build Guide

[Diamond 3] Jungle Vayne - Above the limits [10.16]

Guide by Eizekiels updated August 5, 2020
  • 10.16
Votes: 191
Views: 762,458
LoL Champion Vayne Build Guide

[10.16] An Alternate Angle: Q-Max Crit Vayne Guide

Guide by crabbix updated August 5, 2020
  • 10.16
Votes: 17
Views: 28,748
LoL Champion Vayne Build Guide

[10.16] In-Depth Vayne Build and Gameplay Guide

Guide by thelolbeast updated August 7, 2020
  • 10.16
  • In-depth
Votes: 9
Views: 33,674
LoL Champion Vayne Build Guide

[10.16] Duskblade Vayne: A New Meta

Guide by Seth346 updated August 9, 2020
  • 10.16
  • In-depth
Votes: 12
Views: 11,635
LoL Champion Vayne Build Guide

Season 10 - Vayne Guide - 10.15 Patch [Ready] [Updated]

Guide by Proxxii updated August 2, 2020
  • 10.15
Votes: 2,404
Views: 9,956,148
LoL Champion Vayne Build Guide

Sanun's Diamond Hail Of Blades Vayne [TOP & BOT]

Guide by sanun updated July 9, 2020
  • 10.14
  • In-depth
Votes: 126
Views: 614,085
LoL Champion Vayne Build Guide

[ADC] Vayne Guide Patch 10.14

Guide by Twiggymocha updated July 13, 2020
  • 10.14
Votes: 14
Views: 24,760
LoL Champion Vayne Build Guide

Vibin with Vayne

Guide by PentasForDays updated July 16, 2020
  • 10.14
Votes: 13
Views: 20,603
LoL Champion Vayne Build Guide

[10.13] Diamond Vayne

Guide by NediHere updated June 26, 2020
  • 10.13
Votes: 35
Views: 33,481
LoL Champion Vayne Build Guide

Vayne Guide | Build & Runes | 10.11 Patch [Updated]

Guide by Zoodyacc updated June 11, 2020
  • 10.12
  • In-depth
Rating Pending
Views: 12,927
LoL Champion Vayne Build Guide

[S10.10] ADC Vayne, the Night Hunter - Lategame has Arrived

Guide by atonementblade updated May 13, 2020
  • 10.10
  • In-depth
Votes: 30
Views: 137,620
LoL Champion Vayne Build Guide

Midorima's Vayne Guide (Patch 9.1) | THE SAUCE

Guide by Midorima updated March 20, 2020
  • 10.6
  • In-depth
Votes: 70
Views: 68,467
LoL Champion Vayne Build Guide

(Portuguese Guide) High elo Main Vayne guide Patch 9.24 (g

Guide by Falllol updated December 16, 2019
  • 9.24
Votes: 8
Views: 11,953
LoL Champion Vayne Build Guide

Season 9 Vayne guide! Purge With Silver (9.23)

Guide by Laverenz updated November 27, 2019
  • 9.23
  • In-depth
Votes: 19
Views: 47,494
Season 10 Builds
LoL Champion Vayne Build Guide

10.16 Ranked Guide, Runes and Build ADC Guide (Youtube Climb

Build by ChaseMorePlz updated August 5, 2020
  • 10.16
Rating Pending
Views: 4,955
LoL Champion Vayne Build Guide

The Off-meta power ( Crit Vayne )

Build by Guest updated July 26, 2020
  • 10.15
New Build
Views: 226
LoL Champion Vayne Build Guide

Best Vayne Top Builds/Runes Challenger

Build by Homerjsinpso updated July 30, 2020
  • 10.15
New Build
Views: 345
1 2 3 4 5 6 7 8 72 137

Best Rune Builds for Vayne ADC

If you're looking for the best rune build for Vayne we've got you covered. Below you can find the most recommended rune build for Vayne ADC, as determined by LeagueSpy's calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Vayne this is a great resource to quickly get a good rune selection for Patch 10.16. However, if you are a new Vayne player we highly recommend reading through some of the guides above to learn why these runes are strong on Vayne!

51% Win Rate
Vayne's Rune data is provided by LeagueSpy.gg

Vayne's Most Common Bot Lane Matchups

Find Vayne's relative advantage in their most common matchups! When you're starting a game of League of Legends you should always keep in mind if you'll be at an advantage or disadvantage against your opponent, so you can know whether to bully them or play safe. You can find detailed breakdowns of each matchup on CounterStats, and you can also check out some Vayne guides to see how to build and play against other champions you may find yourself up against!


This counter data is for Vayne ADC in Plat+ games. The win percent shown is the enemy champion's win rate against Vayne.

Vayne's counter data is provided by CounterStats.net
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