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Vayne Build Guide for League of Legends

Champion guides for the League of Legends champion Vayne. Find the best Vayne build guides for S10 Patch 10.21. Our authors will teach you which items to build, runes to select, tips and tricks for how to how to play Vayne, and of course, win the game! MOBAFire shows the top rated guides per patch, but can also be sorted by other criteria such as all-time score, author rank, or newest guides. You can also find other League of Legends Champion Guides.

VayneThe Night Hunter

90% ADC More Details
Win
Rate
52%
Ban
Rate
11%
Pick
Rate
15%



Season 10 Guides
LoL Champion Vayne Build Guide

Vayne: The On-Hit Abuser (Patch 10.21)

Guide by ifound1dollar updated October 14, 2020
  • 10.21
  • In-depth
Votes: 608
Views: 1,928,496
LoL Champion Vayne Build Guide

<Grandmaster> LostFish - Vayne: The Guide

Guide by LostFishEU updated October 18, 2020
  • 10.21
  • In-depth
Votes: 72
Views: 204,620
LoL Champion Vayne Build Guide

Vapora Dark In-Depth ADC Vayne Guide Season 10

Guide by Vapora Dark updated October 14, 2020
  • 10.21
  • In-depth
Votes: 1,800
Views: 9,406,833
LoL Champion Vayne Build Guide

[10.20] An Alternate Angle: Q-Max Crit Vayne Guide

Guide by crabbix updated October 16, 2020
  • 10.21
Votes: 21
Views: 44,710
LoL Champion Vayne Build Guide

[Diamond 3] Jungle Vayne - Above the limits [10.20]

Guide by Eizekiels updated October 11, 2020
  • 10.20
Votes: 199
Views: 789,277
LoL Champion Vayne Build Guide

[Season 10] Hypercarry Vayne ADC guide [IN-DEPTH]

Guide by LouisGeert updated October 5, 2020
  • 10.20
Votes: 18
Views: 17,129
LoL Champion Vayne Build Guide

Season 10 - Vayne Guide - 10.21 Patch [Ready] [Updated]

Guide by Proxxii updated October 13, 2020
  • 10.20
Votes: 2,432
Views: 10,048,996
LoL Champion Vayne Build Guide

The Quintessential Vayne Guide: Walls, Rings, and Late Game

Guide by TheRealVayneGod updated October 12, 2020
  • 10.20
Rating Pending
Views: 7,228
LoL Champion Vayne Build Guide

[10.20] Top Lane Vayne: Abusing CDR

Guide by Seth346 updated October 5, 2020
  • 10.20
  • In-depth
  • Stream
Votes: 16
Views: 22,938
LoL Champion Vayne Build Guide

[10.19] In-Depth Vayne Build and Gameplay Guide

Guide by thelolbeast updated September 29, 2020
  • 10.19
  • In-depth
Votes: 10
Views: 39,816
LoL Champion Vayne Build Guide

Sanun's Diamond Hail Of Blades Vayne [TOP & BOT]

Guide by sanun updated August 21, 2020
  • 10.17
  • In-depth
Votes: 127
Views: 631,752
LoL Champion Vayne Build Guide

Vayne Carry All Lanes.

Guide by HumoLoco updated August 10, 2020
  • 10.16
Rating Pending
Views: 3,577
LoL Champion Vayne Build Guide

Vibin with Vayne

Guide by PentasForDays updated July 16, 2020
  • 10.14
Votes: 14
Views: 21,927
LoL Champion Vayne Build Guide

[ADC] Vayne Guide Patch 10.14

Guide by Twiggymocha updated July 13, 2020
  • 10.14
Votes: 14
Views: 26,140
LoL Champion Vayne Build Guide

[10.13] Diamond Vayne

Guide by NediHere updated June 26, 2020
  • 10.13
Votes: 35
Views: 34,416
LoL Champion Vayne Build Guide

Vayne Guide | Build & Runes | 10.11 Patch [Updated]

Guide by Zoodyacc updated June 11, 2020
  • 10.12
  • In-depth
Rating Pending
Views: 14,473
LoL Champion Vayne Build Guide

[S10.10] ADC Vayne, the Night Hunter - Lategame has Arrived

Guide by atonementblade updated May 13, 2020
  • 10.10
  • In-depth
Votes: 30
Views: 139,715
LoL Champion Vayne Build Guide

Midorima's Vayne Guide (Patch 9.1) | THE SAUCE

Guide by Midorima updated March 20, 2020
  • 10.6
  • In-depth
Votes: 77
Views: 73,829
LoL Champion Vayne Build Guide

(Portuguese Guide) High elo Main Vayne guide Patch 9.24 (g

Guide by Falllol updated December 16, 2019
  • 9.24
Votes: 8
Views: 12,695
LoL Champion Vayne Build Guide

Season 9 Vayne guide! Purge With Silver (9.23)

Guide by Laverenz updated November 27, 2019
  • 9.23
  • In-depth
Votes: 19
Views: 48,207
1 2 3 4 5 6 7 8 73 138

Best Rune Builds for Vayne ADC

If you're looking for the best rune build for Vayne we've got you covered. Below you can find the most recommended rune build for Vayne ADC, as determined by LeagueSpy's calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Vayne this is a great resource to quickly get a good rune selection for Patch 10.21. However, if you are a new Vayne player we highly recommend reading through some of the guides above to learn why these runes are strong on Vayne!

52% Win Rate
Vayne's Rune data is provided by LeagueSpy.gg

Vayne's Most Common Bot Lane Matchups

Find Vayne's relative advantage in their most common matchups! When you're starting a game of League of Legends you should always keep in mind if you'll be at an advantage or disadvantage against your opponent, so you can know whether to bully them or play safe. You can find detailed breakdowns of each matchup on CounterStats, and you can also check out some Vayne guides to see how to build and play against other champions you may find yourself up against!


This counter data is for Vayne ADC in Plat+ games. The win percent shown is the enemy champion's win rate against Vayne.

11,688 Matches 46% Win Rate
10,578 Matches 50% Win Rate
8,695 Matches 50% Win Rate
7,925 Matches 48% Win Rate
7,677 Matches 49% Win Rate
6,817 Matches 46% Win Rate
5,241 Matches 47% Win Rate
4,447 Matches 50% Win Rate
Vayne's counter data is provided by CounterStats.net
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