This post is made with the assumption that you have read and understand these changes:

http://na.leagueoflegends.com/en/news/game-updates/features/upcoming-rune-balance-changes

Introduction

So, first of all, I wanted to give some context on these rune changes. Most people will know what the changes mean on paper, but they will fail to consider the implication of X rune as compared to the gold efficiency of another rune in that type. What we are seeing is the opening up of Seals. Armor seals will not be standard any more. I expect... Read More