Cho'Gath - heals like crazy. Dodge Rupture and you'll be fine. You would need Ignite to kill him by yourself.

Nasus - always, does stupid amounts of damage and heals through everything, except when I play him. You can kill him at level 2 if you have Ignite.

Gnar - You can kill him in mini-gnar form once you get a Phage. Before that dodge his Boomerang Throw as much as you can. Tricky ones will auto a minion and then move towards it and then auto it again as they get closer and then they will toss Boomerang Throw out in order to get their third... Read More