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If you're using several critcal strike chance, and damage runes to make even Jhin giddy, you're going to suffer in your first-clear, during early dueling, and maybe even into the mid-game. You'll become a bottom tier ADC (Which is practically what Kindred is now, an ADC), and it's not really adequate to compete with other junglers, if that answers the question.
Some players run a 1 Crit-Chance Mark, which fine, but I feel as if there's too much chance involved, and I'd rather include a little extra AD, or AS.