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But... I do think that Rylai's is a veeeeeery redundant choice... And I do agree that you need mana regen, so maybe swap Rylai's for a Morello's or an Archangel's (of course, consider prices before the benefits :P)
And please, get the tier 3 runes into your build too :P Even if you list them on your cheat sheet, type "Greater" before the name of the runes and you're set xD
Good luck with it :P
not perfect but a potential guide in the making
you should expand more sections, tips and tricks, how to chase or run away etc.
add some screenshots / videos mayb?
anyways if I was helpful check out my guide down below ^_^
For the rest I suggest that you use the Greater Marks, I wouldn't advise anyone to use Tier 2 runes.
Since you are in midlane, you will have more benefits from Magic Resist than from Armor. That is why I recommend mp/5 Seals and Magic Resist Glyphs.
For items I could suggest
I know Lux very well, ALL of her spells appart from
In this guide you end up with 1525 mana in total with a full build, that makes up for minimal harass if you want to stay when the actual team fight begins.
Also... you're not getting CDR... every, and I mean really each and every Lux should have CDR at LEAST 20%, that is what Lux is all about! Spamming your ult. With a cooldown of 24-30 secs on your ult you will make people litterally rage quit.
Conclution: GET MANA REGEN! Open the game with a
CDR, you really need CDR as Lux get