I disagree, I tried playing a few games based upon your recommendation and it was not as effective. Wit's End is better at Champions late game, but the early game Nashor's Tooth owns the field in that you can kill more minions, more quickly! My experience that means more money and faster upgrades to items. The snowball is much more significant and reduction in mana resist is inconsequential against the minions early game IMHO.

OP,

Your guide has made all the difference. I have just began playing LoL and Teemo is the first toon I have had success with, largely due to your guide. I have a couple of observations and questions. As a new player I am only level 10. I am sure all the characters play a bit differently without the full augmentation of the runes/masteries. That being said, in my selection of items I find Teemo has several issues to overcome and primarily that is HP health, health regen and to a lesser degree mana regen in general, especially early game. With my first Quint I chose HP regen for Teemo. Later on, I will likely change to your suggestions, but to me I feel the runes and mastery choices should help with minimizing your weaknesses, e.g. armor, HP, regens, penetration.

For this reason, I have had most of my success with selecting Doran's Blade and choosing spells Barrier and Heal. I do a lot of running away early game and often the difference is Barrier and Heal so that I can make it to a turret safely. I don't like spending lots of coin on heal pots as early money is so difficult to come buy.

Secondly, because I am squishy and run away, while "lanning" I like to use my shrooms in a non-traditional way rather than warding. I like to place them at the edge of the turrets I am defending and as I push I like to place them in a horizontal line in the lane. Invariably I get hurt and need to run, and the melee folks just love to chase me, as they are already annoyed with me pinging them. I run right over/next to them and as they chase me "boom" they are slowed and I get away, if they follow me into the turret zone, this really hurts them as they can't get out quickly and take even more damage. What is great is after 4 or 5 times of this they finally learn and refuse to chase me. This allows me to escape when needed and the extra HP is needed for those jumpers or slow dealers. Obviously this isn't as effective with ranged folks, but it can still give them problems, especially if you can run fast enough out of their range that they have to follow. So early speed does help. This also helps if I have a partner in lane as it helps them to survive and run away as well. You can tell the opponents get so frustrated with this tactic.

Speaking of speed, I usually take the Berserker's Greaves boots 1) because they are cheap, and 2) early attack speed helps with the auto attacks. Which I think is early key to the game. Later on you can always change out to the mana pen or cc boots Mercury's Treads if needed.

Early game I often struggle, and even though I have wonderful stealth I can't use it to full advantage without HP regen. So say I am wounded and I escape the return fire and need to rest up in relative safely. I would rather not recall if I don't have to, so I sometimes buy the Ancient Coin. It is relatively inexpensive and helps with the most important aspect of the game and what makes this build so successful. With a fast attack speed, and killing minions quickly, you can generate coins quickly. Being able to buy things quickly, farm at a faster pace then your opponents pushes the balance of power into your favor. This will allow you to kill more opponents, which in turn gets you more coins. This is why I try to build as you suggest the Runaan's Hurricane. This changes the Teemo game immensely. Not only does it help you gain coin, but it helps your team immensely by allowing your minions to push further and become a threat. Once I can farm with the Hurricane I sell the Ancient Coin and Doran's for the hat or some of the other items you have suggested. Late game, I feel I need the Spirit Visage or some kind of armor like Banshee's Veil. I haven't tried Zhonya's Hourglass, but if money is no object it may be worth getting.

Now my questions. The only time I had difficulty was going up against Ashe and Fiddlesticks. These guys just owned me and I could do very little. Nasus also can be troublesome. How do you handle these range guys where your blind has little effect? My counter for jumpers is HP, and barrier, with a heal once I can run away.

Great guide, and thanks for writing it.