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For starters, I am really not a huge fan of GLP on Orianna. I struggle to efficiently use the slow on the item without baiting myself into getting much too close to the enemy. For coordinated teams, this slow can be game-changing, but in solo queue it is often a bait IMO.
Also, with the recent buffs to Orianna, I feel like her burst is a little stronger and I like the slightly increased damage in this item. That is not to say that I will not build it in certain situations. I think it is a great counter to champions like Singed, Kalista, ...etc. At the end of the day it comes down to preference and my guide shows mine from personal experience. If I am correct Luden's will become meta even in pro in the near future.
First of all, this rune allows for a lot more skill expression with the additional decision making, but this also brings in the opportunity to make a lot of mistakes. If my summoners are flash-barrier for instance, I will always have the bail out defense of my barrier. But say I swap out the barrier for a teleport, this may have seemed like a good decision to me, but it could also get me killed where I would otherwise survive! Personally, I would want a lot of experience around optimizing this rune before I tried to take it into a ranked game.
Secondly, this rune isn't available until the 6 minute mark. That may not seem like much, but for a champion who is as dominant in the early levels as Orianna, it feels like a waste. There are many assassin match-ups such as Akali where the only real times that you win are pre-level 6. Combine this with my preference to play Orianna in a lane dominant fashion and I definitely sway more towards taking Aery and pushing my early advantage. It really does just come down to preference though.
I was wondering what is the best way to use Minion Dematerializer on Ori? Because after like lvl 9 you already 1 shot the caster minions. Am I still supposed to use it on them? or do i use it on the melees, but even with all 3 on the melees i still don't 1 shot them till much later
The most common way I will use it in lane is to pressure a champion that is poor at waveclearing, especially under turret. Champions like Leblanc and many others struggle to or at least waste a lot of mana to CS under turret. If you simply use the dematerialize to delete cannon minions, you can easily shove large waves and force them under their turret. This will waste their time and mana while giving you a great time to roam or go back to base and return to lane much faster than they can.
So I guess in the simplest form, if you just use it mindlessly on the first 3 cannons, it will create a lot of pressure into your opponent and tilt lane in your favour. There is nothing a twisted fate or a talon likes less than being stuck under their turret while you outscale them. Hope this helps!
While I was reading it, small question crossed my maind. Why did you chosen Spellbinder as somehow prohbited item? It gives a lot of AP and movement speed. Also, it's active effect is very powerfull.
Spellbinder is a really interesting item that I'm honestly still learning the power of. It is a very efficient item in the with how much AP it offers for such a cheap price, but i just don't see it fitting well into a build. What I mean by that is in the standard Mana+CDR->Pen->D-cap/Surivability build path there isnt much room for this item to shine. It can't replace your first item as you would lose lane. I could see it as a possible second item, but in its current state, I still feel Morellonomicon with its flat penetration is incredible on Orianna.
At the end of the day, i just cant justify having it in the place of a Morello,Zhonya or Deathcap. The passive also feels a bit less useful on Orianna since you never really chase down kill like something such as Vlad or Akali.
Hope that helps!