Hello I'm misterfirstblood from EUW and today I'm gonna show you how to play Vayne like gosu does.

This Guide is updated for Patch 13.3 and the final update was at february 9th 2023.

+ Playmaker
+ True Damage
+ Duelist
+ Short cooldown dash
+ Heavy Lategame
+ You will make gosu proud when performing well

- One of the most squishy Champs in League
- Not the best early game
- Short range

Passive: Night Hunter
Vayne ruthlessly hunts evil-doers, gaining 30 Move Speed when moving toward nearby enemy champions.

Q: Tumble
Vayne tumbles, maneuvering to carefully place her next shot. Her next attack deals bonus damage.

W: Silver Bolts
Vayne tips her bolts with a rare metal, toxic to evil things. The third consecutive attack or ability against the same target deals a percentage of the target's max health as bonus true damage.

E: Condemn
Vayne draws a heavy crossbow from her back, and fires a huge bolt at her target, knocking them back and dealing damage. If they collide with terrain, they are impaled, dealing bonus damage and stunning them.

R: Final Hour
Readying herself for an epic confrontation, Vayne gains increased Attack Damage, Invisibility during Tumble, reduced Tumble cooldown, and more bonus Move Speed from Night Hunter

All you need is attack speed to deal tons of damage with Vayne. Her W will do the rest. While Kraken Slayer seems to be the best Option for your mythical item choice, Immortal Shieldbow solves some sustain issues while laning and restores some health while fighting which is why i like it more personally. But this highly depends on the teamcomps, if youre for example with a healer and stomp the lane anyway you can opt to go for Kraken Slayer aswell, as is provides you more damage in late game.

The next best items besides attack speed boots are Blade of the Ruined King Phantom Dancer And Guinsoo's Rageblade. If you really need magic resistance you can replace Phantom Dancer with Wit's End meanwhile.
In late game you pretty much just have to build around survivability, since your damage doesnt come from amazingly high crits, rather from your W ability applying tons of true damage and on hit effects multiple times in a second. So as long as you survive a bit longer in fights, you can deal more damage which is the reason why you literally can build items like Frozen Heart or Randuin's Omen on her without getting reported for trolling.

Lethal Tempo just powercrept all other viable options in Precision tree and since it offers additional attack range i cant really recommend something else either.
Triumph might save your life one or the other time after going all in in a fight while Legend: Bloodline offers you needed sustain. You can also pick Legend: Alacrity to boost your damage if you feel like you won't need that sustain.
Besides that Coup de Grace is a no brainer and should always be taken on vayne as it gives you a huge damage boost.
Treasure Hunter in Domination tree grants you extra gold which makes you scalee faster if utilizing it succesfully while Taste of Blood gives you the much needed sustain.

- Q resets your auto attack animation
- Using Q near to a wall resets Q animation
- Autoattack Q Auto attack E will instantly proc your W so if you see a low health opponent and cant manage to land 3 attacks in a row that might be your combo to finish them off. But pay attention, if they somehow survive it you already used E and they are probably out of range.
This Combo sees the most play under an opponents tower, since the durability patch you cant really afford to tank multiple hits when diving so this combo offers the most "Burst" damage, vayne can offer.
- You can use E and flash after to change/influence your E Target direction.
- Dont Tumble and activate ultimate after or Q is on cooldown until you attacked an enemy
- Use your ult from a brush or hidden spot and walk as far as possible before your first attack to surprise and kill enemies out of nowhere
- You can juke your enemies by activating R + Q and escape in a different direction
- Indeed vayne is a playmaker but remember your main goal is to win the game not creating a youtube montage clip and lose the game (i hope so..?)
- Dont buy Runaans on Vayne. Please :D

Vayne hasn't the best laning phase or the highest attack range and she's not easy ro master neither but if you succesful play your lane or even get a lead its a very rewarding champ.
Imo the biggest advantage you have when playing Vayne is that you dont have to take care about tanks.

Thanks for paying attention to my guide. My English is not the best so if you find mistakes feel free to correct me.
If you wanna see more of my league content or xayah clips check out my channel
http://www.youtube.com/misterfirstblood

or check out my latest video Play Video

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Greetings
misterfirstblood