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Bruiser/AP/General butt-rustling Vladmir (TOP OR MID)
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Introduction to the cone
Your W is an awesome escape mechanic, especially versus skillshotters such as morgana or ahri, or junglers such as Lee Sin, who's skillshot goes right over you, allowing you to get away.
Your E is invaluable. Although it's very easy to get carried away with it, it's a great wave clearing ability, as well as the increase to your regeneration and it's own damage. If possible, get 4 stacks before a team fight.
Your R is amazing. It's what vlad makes the bees knees. The 12% damage buff on enemies is what turns the tides of team fights, and this is why Vlad is seen as such a high priority ban/pick in high ELO/Circuit games.