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Vladimir Build Guide by synczop
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The reason for taking ignite is pretty simple, use it in combination with your ultimate.
Since Vladimir's ultimate(Hemoplague) increases the damage an inflicted target takes by 12%, ignite is a great way to secure the kill.
Your second point should go into your W (Sanguine Pool) just for the utility, allowing you escape any ganks if used correctly. You should max this ability last.
Your E (Tides of Blood) should be taken at level 3 for better farming. keeping the stacks of tides of blood up will help with regeneration effects on you. Max this ability second
Your R (Hemoplague) is your ultimate, and like all other ultimates, take a point at level 6,11, and 16.
9 health per level seals for the extra ability power per level because of Vladimirs passive.
9 Flat magic pen marks
6 Flat ability power glyphs and 3 Flat cool down reduction glyphs. (already explained why you take cool down reduction in the introduction)
3 Flat ability power quintessences
Masteries are pretty basic, just taking one point in attack speed to move you down the offensive masteries.
The defensive masteries will give you health per level and a bonus 30 health points giving you even more ability power from your passive
Thank you so much for checking out my guide, again this is my first one so if you have ideas on how to improve it, go ahead and leave a comment.