Welcome to my first guide for Jax.
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ENJOY!!!

Red Runes:For Red Runes I use Greater Mark of Magic Penetration.It should combine really well with your Empower and Leap Strike Combo.

Yellow Runes:I would prefer you to use Greater Seal of Attack Speed.It should combine good in case you are getting ganked.If I am usually getting ganked I run through a bunch of minions for my Counter Strike.If an enemy is greedy I stun him at my turret and I use Empower and Leap Strike combo.

Blue Runes:For Blue Runes I use Greater Glyph of Ability Power.It will be really useful in early game.

I go on 9/21/0 masteries.These masteries should combine well in early game because of Ardor and Archmage's Sawy.In late game especially in team fights Evasion should be really useful for your team and you not getting killed.

For summoner spells I use Flash.In case of running away or chasing down the enemy Flash could be very useful to kill an enemy.Also with Flash if enemy is on low hp and if he is out of range of your Leap Strike use Flash to catch him and then kill him with Leap Strike Empower combo in case of not killing him with Leap Strike.

For my first item I buy Doran's Shield or in some cases Doran's Ring.It gives you pretty much Health or Ability power which is good for your passive spell.Close to the 10th minute I go to base if I haven't been in base already to buy my Ninja Tabi.After entering into mid game I rush for my Hextech Gunblade and Guinsoo's Rageblade.In late game you should have Trinity Force and Rabadon's Deathcap.That should be around 40th minute.

Always try to focus to last hit minions in early game because of better items and faster leveling.I have around 80% of last hitting minions.Around 100 minions in 15 minutes would be great.

For a think such as team work NEVER go in team fights without 2 or more champs if you do you will probably get killed in less then 5 seconds.For helping defending your jungler or trying to gank one always be close to your friends because in case of dying you could use your Leap Strike to run away.