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The only 3 items what I agree with are: Archangel's staff, Mejai's soulstealer and Zhonya's ring
About runes: WTH?!? armor and magic resist?!? I know his armor is low and he has low hp but you really need it when you have 1000 ability power.
From my side its very bad build.
Main point I wanted to make in this post though is this: ALL good Karthas player should know this, and do this. At the beginning of a team fight, right when things are about to start, or have started, hit your ult. I know this sounds dumb, and morons will say, "why did you hit your ult so early noooob! Now two are barely alive running!" But what they aren't realizing is why your whole team is still alive! You started the team fight with a 3k+ hp buffer! How much easier is it going to take down their whole team if they all have 800-1000 less hp?
Seriously though, if you are not a noob, and not just totally selfish, you do this, and your team will win, not just you.
If you are needing CD reduc, just go kill the golem.
I also don't really agree with rylai's the slow is all but useless, and there are better things for survivabilty and AP out there.
First one was 5/2, second 2/2 (my team got only 4 kills), and third one was 21/4/13.
But if Lay waste triggers a 35% slow on single targets then im all Rylai's, if not then it's a good optional.
btw, I don't think slows stack... say: Wall of pain + Rylai's Slow = Wall of pain
It will take the biggest slow first, then when the biggest slow runs out it will take the longest, which in both cases are ***.