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LeBlanc - Total Burst
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Seals: Greater Seal of Replenishment. Mana regeneration. Great for staying in mid longer. Works well wit health potions. Can be substituted for Greater Seal of Fortitude.
Glyphs: Greater Glyph of Focus. Cool down Reduction. Great for getting you skills off quicker. See skill sequence for more info. You can also substitute this for AP per level runes for her lack of late game skills.
Quintessences: Greater Quintessence of Potency. Ability Power. Great for early game to demolish your opponents.
For escapes i usually do W,R to get out of the way and if needed, E. You can also do E,W,R. Once they are snared dash away wit W and R.