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Malefic DoT 2 shot
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in league of legends in my opinion. You can use call of the void to harass champions and malefic vision on minions to farm and get mana back and when you get nether grasp you can lay down null zone/malefic vision/ nether grasp/ignite to kill a champion. Remember malzahar can really kill someone say if they turret dive you, you can just ultimate them and kill them if someone ganks you ulti if you gank someone ulti