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Malzahar, the Nuke of the Void (MID)
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-Good Damage Output
-Good Magic Pen
-Damages A Lot Of Enemies In A Team Fight
-Squishy early game
Flash is also a great spell both for ganking and running. You could be in a bush, or just farming behind all your minions, then BAM, you're right next to them and you are in range of all your abilities!
Other spells you can use:
-Ignite (if you really need it, e is basically an ignite)
-Fortify (if no one else has it)
Spells to AVOID:
-All the other ones
You want your "auto farm" spell first. Helps you farm and keeps enemy back. You HAVE TO attack the minions a bit too (early game) for it to kill them and spread.
When you lane, your skill shot silence is a good first spell.
Max "Auto Farm" first (Malefic Visions).
alternating between your w (Null Zone) and q (Nether Grasp)
this maintains good damage on your silence (which is better harass than your pool)
Pool is still the most useful when combo nuking.
Of course, grab your Ulti whenever possible.
Your E is a great harass, and does a ton of damage. Put it on the front row minions and watch it spread to the back, and if you're lucky, to the enemy. You can also easily turret dive with this. Just click and run (it's Damage Over Time).
The range of your Q is huge. Also gives you vision. Lengthy silence.
W does a % of enemies max health as damage (capped on monsters). If you actually have 900 AP, it will do 100% of their max health (not calculating resists) if you keep them on it for 5 seconds, but in this build I sacrificed a bit of AP for more magic pen.
Wards are your friends!!!! Which type of ward depends on if the enemy team has any stealth champions or not. Put wards in the bush by the river (if you're laning) or the 2 mid bushes (if you're mid). Later on, put one at barons (just put it through the wall, so you are in no real danger).
Also, if you are laning, try to use your Q 3 times back at base, then go to your lane. This will give you an extra minion (your voidling) for the next time you cast a spell.