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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 2 Guides // Patch 25.11
8.9
646
Votes
51
LoL Champion Anivia Build Guide
LoL Champion Anivia Build Guide

👉 🧊[ NEW SEASON 15 ] - Master's Guide to Midlane ANIVIA! S TIER PICK! 🧊 👈

Guide by RezoneVerified updated May 30, 2025
  • In-depth
8.9
70
Votes
9
LoL Champion Nasus Build Guide
LoL Champion Nasus Build Guide

[25.11] Nasus Mid OTP - Simplest In-Depth Guide S2025

Guide by SurferKiller updated May 29, 2025
  • In-depth
8.9
602
Votes
35
LoL Champion Azir Build Guide
LoL Champion Azir Build Guide

[Season 15] BodyThoseFools' Challenger Azir Guide [In-depth] (10,000,000+ Mastery Points) (Beat Faker)

Guide by Body Those Fools updated May 29, 2025
  • In-depth
8.7
23
Votes
4
LoL Champion Syndra Build Guide
LoL Champion Syndra Build Guide

15.11 My Potential is Limitless

Guide by Demonsedge90 updated May 29, 2025
  • In-depth
8.6
275
Votes
25
LoL Champion Cho'Gath Build Guide
LoL Champion Cho'Gath Build Guide

[Season 14] Sakuritou Challenger Rank 1 Cho'Gath World Guide

Guide by Sakuritou updated June 1, 2025
  • In-depth
  • Stream
8.6
311
Votes
25
LoL Champion Hwei Build Guide
LoL Champion Hwei Build Guide

[Patch 25.11] Hwei Season 15 Guide By Azzapp [Mid/APC/Sup]

Guide by Azzapp updated June 1, 2025
8.3
22
Votes
5
LoL Champion Orianna Build Guide
LoL Champion Orianna Build Guide

25.11 Orianna

Guide by SeMike updated May 29, 2025
  • In-depth
8.3
13
Votes
2
LoL Champion Zoe Build Guide
LoL Champion Zoe Build Guide

[25.10] Zoe Ultimate Matchup Guide

Guide by AnxialSociety updated May 28, 2025
  • In-depth
8.3
525
Votes
68
LoL Champion Swain Build Guide
LoL Champion Swain Build Guide

[ Patch 25.11 NEW SEASON 15 UPDATED!! ] - SWAIN is the GOD OF MIDLANE PAIN! - 🤯

Guide by RezoneVerified updated May 30, 2025
  • In-depth
8.3
66
Votes
9
LoL Champion Zeri Build Guide
LoL Champion Zeri Build Guide

[25.S1.10] Lethality Burst Zeri Mid/Bot Season 15

Guide by RealLrd34 updated May 28, 2025
  • Off-Meta
8
13
Votes
3
LoL Champion Vladimir Build Guide
LoL Champion Vladimir Build Guide

Vlad 15.10+ Item Guide

Guide by KormitLeFrag updated May 31, 2025
8
25
Votes
8
LoL Champion Cho'Gath Build Guide
LoL Champion Cho'Gath Build Guide

[Season 14] Sakuritou Mathematically Correct Cho'Gath

Guide by Sakuritou updated June 1, 2025
  • Stream
7.7
508
Votes
57
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.11] Incursios' Challenger Item Quick Guide to Dominating Mid

Guide by IncursioOCE updated May 30, 2025
7.4
19
Votes
8
LoL Champion Irelia Build Guide
LoL Champion Irelia Build Guide

[25.11] AP Irelia Ultimate Guide

Guide by SkandalloTV updated May 29, 2025
  • In-depth
  • Off-Meta
6.6
16
Votes
10
LoL Champion Yone Build Guide
LoL Champion Yone Build Guide

[Season 14] Sakuritou Challenger Yone Guide

Guide by Sakuritou updated June 1, 2025
  • Stream
6.6
13
Votes
8
LoL Champion Yasuo Build Guide
LoL Champion Yasuo Build Guide

[Season 14] Sakuritou Challenger Yasuo Guide

Guide by Sakuritou updated June 1, 2025
  • Stream
New Guide
LoL Champion Orianna Build Guide
LoL Champion Orianna Build Guide

Orianna community guide

Guide by Jumpman25th updated June 1, 2025
4.8
10
Votes
14
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[Season 14] Sakuritou Challenger Katarina Guide

Guide by Sakuritou updated June 1, 2025
  • Stream
2025, Season 2 Guides // Patch 25.10
10
214
Votes
5
LoL Champion Hwei Build Guide
LoL Champion Hwei Build Guide

[25.10] Your True Colors - Complete Hwei Guide

Guide by Soft Headpats updated May 18, 2025
  • In-depth
10
327
Votes
20
LoL Champion Qiyana Build Guide
LoL Champion Qiyana Build Guide

[S15] QIYANA MID GUIDE - YT GUIDES AT END

Guide by Allyooops updated May 17, 2025
  • In-depth
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AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYuumiZacZedZeriZiggsZileanZoeZyra
Teamfight Tactics Guide