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Spells:
Heal
Flash
Ability Order
Staggering Blow (PASSIVE)
Nautilus Passive Ability
Intro
I give Nautilus these runes not only to give him a quick edge to harass early game with the armor and magic resist, but to also keep the enemy on their toes when they let me get close enough to land a shot of armor pen + Staggering Blow on them. The gold per 10 quints allow for constant gold generation, even if it is at a rate of 3 per 10 sec, but you'd be surprised at the difference that little bit makes with Philosopher's and Heart of Gold the whole game.
For my masteries, I go 0/21/9 to make myself as tanky as I can early on and give me the movement speed from utility to chase down retreating enemies for my carries, even under turrets (but that's for later on *evil laughter*). If you want to jungle Nautilus, I don't know what to say; I don't personally enjoy it so I don't do it.
My items are aimed at giving me very fast gold generation early on in order to keep "my farm up" in a sense. This means that even if you're having a bum start to a game, you can still acquire your items through gold generation and the occasional jungle mob if you keep getting harassed. Keep yourself out of dodge until you get a few items and you'll be set. One alternative to the build ( I haven't tried it but if you want to go for it) may be to swap our your Ninja Tabi for Mercury Treads and turn your Philosopher's Stone into a Shurelya's if you find yourself against more ability power than just physical damage/"auto attackers."
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