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LoL Best Seraphine Middle Build Guides 2025

Build guides for Seraphine Middle on MOBAFire. Find recommended items and runes by high ranked players to learn the best Seraphine Middle builds. Create your own champion guide!



Season 10 Builds
Rating Pending
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

SERAPHINE SUPPORT BUILD

Build by shinypanda updated November 4, 2020
Rating Pending
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

The PLEBS Simple guide to Seraphina (ON HIT/MAGE)

Build by Crash1025 updated October 30, 2020
Rating Pending
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

Seraphine mid

Build by Nthaneq updated October 30, 2020
Rating Pending
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

Diamond Seraphine Midlane Self Peel One Shot Build

Build by haruchhi2 updated October 29, 2020
Rating Pending
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

Sera-Fine

Build by Teaxox updated November 9, 2020
Rating Pending
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

Don't die seraphine

Build by The Vastaya updated November 8, 2020
Rating Pending
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

[v10.22] Seraphine Guide

Build by Forscythe updated November 5, 2020
Rating Pending
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

Seraphine but without GLP

Build by Wicks updated November 5, 2020
Rating Pending
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

Seraphine synergies mid/sup

Build by Advitil updated November 4, 2020
Rating Pending
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

Seraphine midlane bulid

Build by Asspect updated November 1, 2020
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