Ahri

Early Game she will burst you unless you can dodge her spells then you can also burst her but late game you can get tanky enough that you dont die to her and you kill her easily

Zed

One of your easiest match-ups although it is zed your kit with cc counters him hard when he ults you you are tanky enough to survive it and if u are not you can just ult yourself to completely counter his ult

Akali

Anivia

Although it is ice vs ice her kit is farther than yours and trying to burst can result in you getting bursted yourself

Aurelion Sol

Cassiopeia

Her long range plus her poison can really make it so you have a bad time just make sure you stay at a distance until you can for sure lock her down and try to prevent looking at her when she ults

Cho'Gath

Ekko

He can really be a pain since he has a redo button so if facing him just keep poking and harass him for trying to cs if he comes in range to e respect him because that is all he needs to get nice damage on to you just poke from afar in team fights and if he jumps on you or your adc cc him

Fizz

Karma

Karthus

Kassadin

Katarina

This is most likely the easiest match-up for Lissandra your CC stops her from jumping everywhere and her ult is countered by your ult stay safe farm in team fights lock her down so she can not do anything in the team fight

Kayle

Kennen

be careful once he hits level 6 since on pen and paper it seems your level 6 is stronger but his ult still goes off even if you cc him and he has more movement then you which can really be a pain

LeBlanc

Lissandra

Lux

you build more tanky than she does and if she ults you just ult yourself and if you get a chance to ult you can most like burst her and maybe 1 shot her

Malzahar

Morgana

Orianna

Ryze

Syndra

Talon

With most assasins just lock him down so he can not do anything when he roams follow even with tp almost always try to also cut through walls with your e

Teemo

Twisted Fate

Veigar

Vel'Koz

Maybe it is just me but i always struggle with this matchup unless u can get close to him you most likely have a bad time

Viktor

Vladimir

Xerath

Yasuo

This is the one assassin that I have trouble with because he has cc in his kit with does not allow you to either protect yourself or lock him down stay safe poke to get his shield and in team fights make sure he is useless

Ziggs

Zilean

Zyra