I use Vayne mainly as an anti-tank unit. However, with this build she is able to deal with non tank units as well.

One of the biggest problems with this build is her lack of health and armor. Therefore, during a team battle I try to draw the tank away from the team or let my teammates initiate the battle and take the blunt of the damage, then I come in and clean up the rest of the players.

This tactic may seem a bit cowardice. However, a tank that is played correctly will usually be the last person alive and this tactic will allow you to obtain a lot more kills a lot less deaths.

The spells I use are flash and rally.

The reason I choose rally is because Vaynes' tumble ability adds extra damage based off of her attack damage. In the beginning levels and sometimes later levels this extra attack damage might make the difference between life or death.

The reason I choose flash is to catch other people that flash and to flash over obstacles to catch or run away from other people. Another advantage of flash that i commonly use is for harassing. I do this by tumbling towards an opponent shooting them and then flashing away to avoid any spells or attacks. Since flash does have a rather long cooldown this technique is used mainly for when opponents are close to their turrets and low on health or are behind another opponent and are low on health.

I use 21/6/3 as my main set up. It is directed more towards dealing more damage faster and being able to use your abilities a lot quicker. This comes in handy when you need to tumble after someone but have about .1 second left on your cooldown. It helps by reducing cooldown times so they will be ready when you are.

However, I have also gone with an 3/6/21 set up. This set up is directed more towards your spells and speed. It allows you to reduce your cooldowns by a greater amount but you wont do as much damage as the 21/6/3 set up. However, if you find yourself in those .1 second cooldown time moments then this will allow you to tumble towards the opponent more often, this can also help your harassment game.

I grab tumble first so i can harass the opponents and perhaps tumble in for a close turret kill. I then get silver bolts so I can do that extra damage every three hits. Next I get Condemn. I get this just in case we get into a low level fight I can knock them against the wall stun them and save them for later. After that i master Silver bolts (stopping for a point in Final Hour at level six) so that it does increased damage and is even deadlier towards tank units. After mastering that and finally having Final hour I master tumble so that when i need that little bit of extra damage i use Final Hour then Tumble and get the max amount of extra damage i can. Lastly I master Condemn. The increased damage that you get from it is not worth it in lower levels and therefore is saved till you have more attack damage.

I get the armor pen marks/quints so that I can pierce through almost all of the low level characters armor and do almost all of my damage directly to them. I then get attack speed seals so that I can use my Silver Bolts passive faster. I get magic resist Glyphs just in case they have mages in my lane.

To start I go with the basic boots so that I can catch the opponents and health vials because vayne has very little health in the beginning of the game. I later get the boots of swiftness so I can better catch opponents. After that comes the phantom dancer so that my silver bolts passive is triggered a lot quicker. Next comes the black cleaver. this adds to your attack speed and allows you to pierce even more armor which most tanks will have lots of. I then get the Bloodthirster for the damage and the life steal (which will come in handy during team battles and turret diving). Next comes what I think is the most important item of the build , the Bloodrazor. Not only will you silver bolts passive do damage based off of the opponents health but now every attack will. This will take huge chunks out of your opponents health bar. The last item is the frozen mallet. This can be replaced by any other item of your choosing, however, I use this mainly so i can catch my opponents if they have haste or are faster than me.

I use her as an anti-tank unit with the ability to destroy any other unit in her path. although she is a bit squishy and if left alone can be easily ganked and killed. I use her mainly as the clean up crew. I help out in the team battles by stunning units where i can but tend to stay back as to not get killed or close to death. Then I go in and clean up the people low on health or chase after the ones that my teammates cant catch and finish the job.